Why 2025 matters for TRT
In early 2025, the FDA updated labeling for prescription testosterone products to reflect new safety data, including results from the TRAVERSE cardiovascular outcomes trial. The trial found TRT was not associated with higher major adverse cardiac events vs. placebo in appropriately diagnosed men, though labels still highlight considerations like blood pressure and certain clotting/arrhythmia risks. U.S. Food and Drug AdministrationUrology Times
Who’s a good candidate?
- Men with symptoms consistent with hypogonadism and repeatedly low morning total testosterone (often <300 ng/dL), after other causes are evaluated. American Urological AssociationEndocrine Society
Potential benefits you may notice
- Improved libido and sexual satisfaction
- Better mood/energy, reduced anemia, increased lean mass and bone density in some men
Outcomes vary; your baseline health and lifestyle still matter a lot. Endocrine Society
Risks and monitoring in plain English
- Cardiovascular: TRAVERSE showed non-inferiority for major events, but labels now emphasize BP monitoring; discuss history of clots or AFib. U.S. Food and Drug AdministrationUrology Times
- Erythrocytosis (high hematocrit): can raise clot risk—requires periodic labs. Endocrine Society
- Fertility: Exogenous T suppresses sperm production—flag this if you want children. Endocrine Society
- Prostate considerations: Shared decision-making on PSA monitoring; TRT doesn’t appear to cause prostate cancer, but vigilance is standard. American Urological Association
Forms of TRT: finding your fit
- Injections (weekly/biweekly or more frequent micro-dosing): predictable, cost-effective
- Topical gels/solutions: daily; avoid transfer to others
- Pellets: procedural, long-acting
Your provider will match route, dose, and follow-up to your goals and labs.
What your first month at MVP looks like
- Morning labs (TT ± free T, CBC, SHBG, others as indicated)
- Consult + plan (risks, benefits, fertility goals)
- Start lowest effective dose + BP/hematocrit plan
- Follow-up labs at ~6–8 weeks; adjust for symptom relief and safe ranges
Ready to talk through TRT with real data? Book a consult at MVP Men’s Clinic.